… 1b are often treated with granulocyte colony stimulating factor (G-… preferential expansion of
the preexisting monosomy 7 cell … spliced G-CSF receptor isoform with demonstrable abnormal …

… its receptor granulocyte colony-stimulating factor receptor (… which isoforms are expressed
in non-hematopoietic cells, … ) and class IV (differentiation defective) GCSFR isoforms are …

… use of high doses of granulocyte colony-stimulating factor (G-CSF) … Preferential stimulation
of cells carrying −7 by cytokines has … receptors. However, it is not fully understood why such a …

… growth in comparison to the Class I isoform. The Class III … Another pathway that inhibits
internalized CSF3R involves the ER-… IV granulocyte colony-stimulating factor receptor isoform …

… encodes the granulocyte colony stimulating factor receptor (G… SRSF2 P95 mutations have
been shown to preferentially bind to … had demonstrated selective growth of monosomy 7 cells …

… link between thrombopoietin receptor signaling and cytogenetic … cyclosporine with
granulocyte-colony-stimulating factor (G-… dL, and a platelet count of 2.8×10 4 /μL before treatment …

… are granulocyte colony stimulating factor 3 (CSF3/GCSF), … Class IV were also observed
in patient cells with monosomy 7, … were seen to be preferentially associated with alternative …

… human granulocyte colony-stimulating factor can improve … increased expression of the
Class IV isoform in patients with … Interestingly, monosomy 7 is the most common cytogenetic …

… abnormalities is also associated with poor outcomes 4, 5 and in MDS, MK+ is strongly …
granulocyte colony–stimulating factor preferentially induces proliferation of cells with monosomy 7 …

… growth factors, especially granulocyte colony-stimulating … the monosomy 7 clone, suggesting
the transformed monosomy … may be preferentially stimulated by EPAG to proliferate. One …